over 100 Links on this page = 21st Century Bibliography.

 

 The AntiAging & Longevity Project was founded in 1998 by a baby boomer Registered Nurse (DOB: 1946)

rhGH (recombinant human Growth Hormone, Somatropin) is a bio-synthetic FDA approved prescription hormone replacement medication that is rDNA derived & bio-identical w/ 191 amino acid sequence endogenous Anterior Pituitary secreted hGH (Somatotropin)

Health and Quality of Life define Wealth.

You're never to old to become Healthier & Wealthier.

 

NYSE Pharmaceutical Company literature on Adult rhGH (Somatropin)Eli Lilly (NYSE:LLY) Humatrope®,  Pharmacia-Upjohn (NYSE:PNU) Genotropin® Merck-Serono (NYSE:MRK) Saizen® Sandoz (NYSE:NVS) Omnitrope®,  Genentech (NYSE:DNA) Nutropin®

 

Adult rhGH auto-injection devices.

The Endocrinology of Aging: Many age associated mental & medical conditions are based in declining endocrine  function.

  • At 40 endogenous GH is about 75% that of a 25-30 year old ... production is 25% less & maybe you feel a little different.

  • At 50 endogenous GH is about 55% that of a 25-30 year old... the 45% decline combines with accumulated deficit & you feel it.

  • At 60 endogenous GH is about 40% that of a 25-30 year old... a 60% decline + the effects snow ball.

2008 marks 50 Years of Doctor Prescribed injectable hGH Therapy.

  • In 1958 Tufts University School of Medicine researcher Dr. Maurice Raben treated a 17 year old patient with Growth Hormone extracted from cadaver Anterior Pituitary glands.

  •  Natural Anterior Pituitary hGH is Somatotropin Somatotropin had the potential to cause Crutchfield-Jacobs Disease, CJD, which is similar to Mad Cow Disease.
    • Creutzfeldt-Jakob Disease (CJD) is the human form of spongiform encephalopathy, the bovine form of spongiform encephalopathy is commonly known as Mad Cow Disease.  Both are transmitted through contaminated Central Nervous System material.  From 1958 - 1985 Somatotropin was extracted from cadaver brains & was a source of contaminated CNS material.

  • 1985: Bio-Tech giant Genentech patented 1st generation biosynthetic rhGH Somatrem, methionyl-growth hormone or met-GH.  Biosynthetic Somatrem ended the potential of CJD, Crutchfield-Jacobs Disease. Somatrem met-GH is a 192 amino acid molecule.

  • The Anterior Pituitary secreted hGH molecule, endogenous Somatotropin,  has191 amino acids in a specific organic structure. 191 Amino Acid Sequence designates the position each of the 191 amino acids holds in the human GH molecule's amino acid structure. (A change of even 1 amino acid alters the molecule's properties.)

  • 1993-2008: Genentech's second generation biosynthetic rhGH, Somatropin, is rDNA derived & bio-identical w/ the 191 amino acid sequence of Anterior Pituitary Gland secreted endogenous human Growth Hormone, Somatotropin.

Like Mr. Nietzsche reputedly stated . The doer alone learnth.

We could be divided into 3 groups:

  1. Those who are optimizing their personal situation

  2. Those who want to optimize their personal situation

  3. Those who 'wish' they wanted to optimize their personal situation

It's not the men in my life, it's the life in my men. ~ Mae West...      or the life in my woman! ED

April 18, 2008. LA Chronicle: The hormone injections have proven to offer amazing benefits

Dr Ronald Klatz of the American Academy of AntiAging Medicine, “Nearly 20,000 clinical studies conducted around the world document the broad benefits of pharmacological hGH therapy. "

February, 2008: Dr. Andre Berger reports that in his LA Clinic, "... human Growth Hormone therapy (rhGH) for the treatment of adult growth hormone deficiencies has helped thousands of my patients, men and women, feel more energetic and more vibrant."

& This second Mayo Clinic report provides a list of aging symptoms with the whys.

April 22, 2008: NBC News: Mainstream Physicians Join Anti-Aging Movement. 

hGH may not improve a young athlete's performance, a young ballerina's bas or a young pianist's concerto.

Will rhGH improve a 40+ year old player's fastball or homerun swing?

 hGH Books from Amazon.com

Feb 11, 2008 Roger Clemens Congressional Baseball Committee:  Proper adult use of growth hormone is effective & safe

  • hGH will definitely help baby boomer athletes, ballerinas & pianists achieve a leaner body mass.

  • hGH will definitely help baby boomer athletes, ballerinas & pianists achieve better mood & attitude.

  • hGH will definitely help baby boomer athletes, ballerinas & pianists increase their endurance.

hGH increases energy levels and metabolic rate, boosts libido and improves mental well being.

Baby Boomer Actresses that remain youthful Madonna, Demi Moore, Pamela Anderson, Jennifer Aniston and Debbie Harry, are reported to being treated with doctor supervised prescription human Growth Hormone

April 2003, World Health: a 2 year study on a large group (148 individuals) of adult patients demonstrated the beneficial effects of rhGh on body composition, metabolic parameters and general well-being.

  • An additional health benefit of rhGH was a drop in sick days & hospitalization = improved immune function.

2006, European Journal of Endocrinology: Seven years of rhGH treatment resulted in persistent beneficial changes. The broad physical improvements remained present for the entire 7 years of rhGH treatment.

  • The 2006 Journal of Endocrinology report demonstrated lowered blood pressure, improved total cholesterol & HDL + improvements in body composition.

April, 2008, Journal of Clinical Endocrinology: Persons with low hGH levels are at increased risk of cardiac disease. The cardiac benefit is related to the endothelial effect hGH & NO have on the vascular system.

Elmer M. Cranton, MD, Safe hormone levels at age 30 will remain safe when restored to that same level later in life.  Adverse effects generally result from excessive doses.

 

 "HGH" Sprays are stupid!

 

Hormonal demise is often responsible for the physical & cognitive issues experienced with aging.

  1. Low energy / motivation
  2. Muscle loss
  3. Fat gain / weight distribution (truncal / belly / hip obesity)
  4. Attitude / mood issues

Natural Anterior Pituitary hGH is Somatotropin Somatropin is rhGH.  Both are 191 amino acid chain hormones.

  • 1981's 1st Generation biotech Somatrem is a 192 amino acid sequence molecule.

  • '95-'08, 21st Century 2nd Generation biotech rhGH Somatropin is the bio-identical 191 amino acid sequence molecule as Somatotropin.

  • 2008: rhGH Somatropin is dispensed under assorted Trade Names.

  • 3rd Generation rhGH, long lasting, is in Second Phase FDA Testing.

Several rhGH Somatropin brands come pre-mixed in an easy to administer auto-injection device.

  1. All 3: dial your prescription .. 

  2. Press against your skin & click the 'ball point pen like button' ..

  3. Feel pressure on your skin & hear the injection device  'click'.

  4. Genotropin Pen® Injection Device Video: Step by step video instructions for the Genetropin Pen (Pharmacia-Upjohn Somatropin)

     

    Omnitrope Pen® Injection Device video:  Step by step video instructions for the Omnitrope Pen  (Sandoz Somatropin)

     

    Saizen Cool Click® Injection Device. (Merck-Serono Somatropin)

            

2006: Dr. Richard A. Rydze    1972: Olympian "Dickey" Rydze.

Med Student "Dickie" Rydze was the Silver medallist in platform diving at the 1972 Munich Olympic Games (1972 Munich Olympics: Terrorist attack on Israeli athletes & Mark Spitz's 7 gold medals).

Young med student Dickey Rydze was topped only by 3 time Olympic Platform Diving winner Italian Klaus Dibiasi.  Professional Olympian Dibiasi won a total of 5 Olympic gold medals & barely topped young Dr. Rydze.

A team doctor for the NFL's Pittsburgh Steelers, Dr. Richard A. Rydze, reports that he prescribes AMA & FDA approved  rhGH & Testosterone HRT for older patients in his private practice.

  • Dr. Richard Rydze's private practice is as a doctor of internal medicine at the University of Pittsburgh Medical Center.

  • Dr. Rydze reports that he prescribes testosterone gel cream and daily injections of  rhGH, recombinant bio-identical Human Growth Hormone, for patients in their 50s and 60s.

  • Medical director for the charitable Little Sisters of the Poor Nursing Home

  • Medical director of the Community College of Allegheny County

  • Medical director of the FBI's Pittsburgh office

  • Senior aviation medical examiner for the Federal Aviation Administration.

Benefits of Adult rhGH Therapy.

  1. Reduced body fat / Improved body composition
  2. Increased energy.
  3. Improved libido.
  4. Improved immune function.
  5. Stronger bones.
  6. Lower cholesterol.
  7. Lower blood pressure.
  8. Faster wound healing.
  9. Smoother, firmer skin.
  10. Elevated mood.
  11. Improved cognition.

April 18, 2008. LA Chronicle: The hormone injections have proven to offer amazing benefits

Dr Ronald Klatz of the American Academy of AntiAging Medicine, “Nearly 20,000 clinical studies conducted around the world document the broad benefits of pharmacological hGH therapy. "

February, 2008: Dr. Andre Berger reports that in his LA Clinic, "... human Growth Hormone therapy (rhGH) for the treatment of adult growth hormone deficiencies has helped thousands of my patients, men and women, feel more energetic and more vibrant."

& This second Mayo Clinic report provides a list of aging symptoms with the whys.

 

How to chose the best doctor for your specific needs. 

AntiAging Medicine is often referred to as Aging Management Medicine.  A realistic goal of an AntiAging program is to delay the onset of & to slow the progression of Aging's Symptoms

A Patient's Advocate Medical Provider / Doctor is necessary for optimized aging.

The better the Doctor the better the examination room communication.   2 way communication. A good Doctor listens.

Doctor shopping to achieve your personal goals is 100% acceptable.

  • Modern HMO doctors are often corporations that see up to 15 patients per hour.

  • HMO Doctors are often not dedicated to individualized medicine orpersonalized patient care.

Demand personalized medical care!!!

Choice of medical care provider should not be a random pick

& certainly not a decision delegated to a HMO.

Women's International Pharmacy can provide a list of competent doctors by state.

Google

  • Go to Women's International  Pharmacy web site's "resources" page

Women's International dispenses Bio-Identical 191 sequence Saizen®  + is an extremely efficient pharmacy 

  • .. speak to a pharmacist at any time ..  max 30 second wait.

"If I'd know I was going to live this long I'd taken better care of my self" ~ Mickey Mantle (1931-1995)

Mayo Clinic Human Growth Hormone report demonstrates hGH's benefits:

Bolster the heart's ability to contract

Improve mood and motivation

Increase exercise capacity

Increase muscle mass

Increase bone density

Decrease body fat

Primary factors for an early demise:

  • tobacco

  • alcohol

  • obesity

  • high-blood pressure

  • high cholesterol

  • poor diet

  • lack of exercise

most are personally or medically controllable.

Most stupid choices are fairly obvious mistakes.  Doh!

stop smokin', drink intelligently, exercise .. & use protection when you should

we have only 1 dietary rule: Eat nothing today that you will regret eating tomorrow.

Tobacco kills the equivalent of 30 x 747 hijackings per day

Cigarettes kill more than 3  9/11s  per day!

Erectile Dysfunction is 40% more likely among smokers.

June, 2008.  Us News & World Report: Restful sleep is associated with healthy / successful  aging.

You have to stay in shape. My grandmother, she started walking five miles a day when she was 60.  She's 97 today and we don't know where the hell she is. ~Ellen DeGeneres

  • Green Dash =Insulin
  • Yellow Line = Blood glucose
  • Red Line = HGH
  • Orange Line = Average Glucose

There are positive hormonal responses 

with both aerobic and anaerobic exercise.

 Dr. Ronald Klatz' 1998 book Grow Young With HGH is the Amino Acid Secretagogue Bible.

"HGH" Sprays are stupid!  Spray "not-HGH" in nanograms(ng)=.000000001 gram(billionth!)="drops in an Olympic pool". No way, José!

Amino Acid  Secretagogue "Releasers" work.  The Aminos must be present in grams not milligrams(>20 pills) + protocol adherence

Secretagogues: Amino Acids that stimulate the endocrine system to increase hormonal secretions.

Directions on how to make your own custom nutritional stack.  You can design / make  a 1st thing in the morning stack, pre-workout stack, post-workout stack and pre-sleep stack.. each  customized  for time of day & situation.  By mixing your own stacks you can optimize for your metabolism or goals.

  • If you have a damaged Anterior Pituitary or Hypothalamus gland Secretagogues will not work for you.  These glands must be intact for the Secretagogue supplementation to work.

  • By combining specific amino acids and other synergistic nutrients we can trigger desired responses by specific glands. 

    • The basis for increasing the Human Growth Hormone level is the use of HGH releasers or agonists.

  • Secretagogues are substances that stimulate the endocrine system to increase growth hormone secretions.

    • One would be hard pressed to find a 21st century exercise or nutrition publication that does not tout the benefits of amino acid supplementation.

  • Amino Acid Nutritional Stacks based on published research.

  • Amino Acid HGH Secretagogue products that are comparable to the recommendations cited in Dr. Klatz' 1998 research, published in his 1998 book, "Grow Young With HGH".

    • A 300+ page book providing supporting lab work & extensive research procedural documentation.

    • There are numerous books on the effectiveness of amino acid Secretagogues.  Dr. Klatz, Dr. DiPasquali, Sandy Shaw & Dirk Pearson all have books out with supporting lab work.

  • There is a consensus that dietary control & proper exercise are important for success.

2005 Syracuse University: Dr. Jim Stoppani, Flex Magazine: A Research Project on men between 18 & 35 has published a report showing that that 6 grams to 9 grams of Arginine acts as a HGH Secretagogue.  A 9 gram L-Arginine serving increased serum HGH by over 60%,  from 4mcg/liter to 6.5 mcg/liter.

Amino Acids are the building blocks of protein and perform many specialized functions.

Sylvester Stallone discusses using rhGH in preparation for his new Rambo movie.

It's impressive that 61 year old Sly Stallone is still authoritative as Green Beret John Rambo

  • View a Stallone interview & compare his energy & presence with the average 61 year old kodger

  • Impressive!

"Everyone over 40 years old would be wise to investigate adult HRT because it improves the quality of your life."  rhGH Advocate Sylvester Stallone in People Magazine.

The University of California at San Francisco is naming it's new research center after rDNA derived Growth Hormone pioneer, William J. Rutter

  • The William J. Rutter Center is situated on the UCSF campus across from Genentech Hall, the campus' other major research building.

    • Genentech Hall is part of a legal settlement. 

    • UCSF won a court decision that rhGH was developed on the UCSF campus & that Genentech owed UCSF part of Genetech's $2,000,000,000. profit on rhGH.

    • Genentech Pharmaceuticals patented biosynthetic Insulin in 1982 as well as patenting biosynthetic hGH in 1985.

    • 2008: Genentech Pharmaceutical (NYSE:DNA) remains the leader in HGH research holding the 1993 patent on Somatropin.

  • The University of California San Francisco Geriatric Resource Center. Information all baby boomers striving to be educated about their personal status should review.

    •   check it out! .. must say it makes us feel good!

Without lifestyle changes 25% of all people born today will develop Type 2 Diabetes.

Exercise and weight control can reduce Type II Diabetes by 60%

Considering Testosterone Therapy?

A man 40 years old has less than 1/2 the testosterone a man of 25 has.

Testosterone replacement therapy may help elderly men with mild Alzheimer's disease.  The University of California, Los Angeles team found that replacement hormone therapy significantly improved quality of life for Alzheimer's patients.

Alzheimer's: The Baby Boomer Nightmare.

Projections for 2050 Alzheimer's care far exceed the costs of the Iraq War.  The only projected cure at this point involves stem cells.

AntiAging Medicine as a specialty was founded in the early '90s .. as we baby boomers with 'incredibly high expectations' started hitting the 'middle age wall'.

The issue of hormone replacement should be addressed by any comprehensive medical plan for baby boomers.

  • Ask anyone speaking poorly of proper HRT, "what effect of the program did you personally find negative?"

  • $s to donuts .. they have not prescribed / administered or been on an appropriate HRT program.

21st century medical studies from several American University Medical Schools, summarized & linked to below, document that hormone replacement therapy is a valid medical protocol..

New England Journal of Medicine. THE 1990 report: "Diminished secretion of growth hormone is responsible in part for the decrease of lean body mass, the expansion of adipose-tissue mass, and the thinning of the skin that occurs in old age. "(N Engl J Med 1990; 323:1-6.)

Current consensus is to withhold growth hormone from patients with cancer.

A low calorie diet is on your route to graceful aging

The first step is the hardest step!

Again, many of the most problematic symptoms of aging are effectively treated with Hormone Replacement Therapy.

  • LONG TERM RESEARCH demonstrates that estrogen replacement affords protection against Alzheimer's, the most benefit occurs if treatment is begun at or near the onset of menopause.

  • HGH and Testosterone can provide an improved quality of life.  FACT!

  • 0ver 50% of Testosterone is produced from DHEA.

2004, Journal of the American Medical Association:  University of Chicago Researchers found that the first stage of age-related deterioration of sleep quality in men occurs between the ages of 25 and 45. They're sleeping as long as younger men, but they're spending less time in restorative deep sleep.

There is strong relationship between sleep quality and physical and mental health Proper rest is critical.

Many of the health issues, age related medical conditions, middle-aged persons begin to experience are directly related to diminished hormone production.

Long term medical research HAS BEEN COMPLETED regarding hormone replacement & antiaging.

July 29, 2003. Human Growth Hormone Gets New FDA Approved Use

 The Food and Drug Administration has OK'd the use of growth hormone for children who are healthy but abnormally short and who hope to gain 1 to 3 inches of height.*  ( *Our focus is for adult benefit only.)  News article link.

We get many calls from adults wanting to gain height.  After the growth plates on long bones is mature the height growth process has pretty much complete.

  • US Government FDA site: FDA Approves Humatrope ( E. Lily's brand name rhGH ) for Short Stature

  • Previously HGH has been approved to treat both adults & children for low HGH production by the Anterior Pituitary.

  • Now HGH is US FDA approved to treat 'shortness' determined to be unrelated to endocrine function.

Persons under the care of a Physician, on complex medical plans or taking multiple medications should always consult with their Physician before any dietary or nutritional supplementation changes are made. Current cancer patients, cancer patients in remission and previous cancer patients should consult with their Physician before considering any new exercise or nutrition program.

A medical check up is advised before beginning any nutritional, dietary or exercise program.

Realistic assessment of your current physical condition, to include genetics as well as wear & tear.

Directions on how to make your own custom nutritional stack.

In the 'old days' (60s, 70s & 80s) HGH was obtained from the pituitary gland of cadavers & there were possible negative effects & complication

Modern rhGH (recombinant HGH ) is a very safe prescription medication, especially when proper labs are utilized to monitor hormone levels to ensure proper dosage.. Based on proper lab work,  primarily IGF-1, prescription HGH is an appropriate medical treatment.